Endocrine Abstracts

Introduction: Intermittent Cushing’s syndrome is characterized by alternating episodes of hypercorticism with periods of eucorticism. It is a rare but well-defined entity and should be known. It remains a diagnostic challenge sometimes particularly difficult in endocrinology, we report a case.Case presentation: A 22-year-old diabetic patient on metformin, who consulted us because of a weight gain with the appearance of stretch marks for 2 months. Th...

Introduction: Cushing disease is the most common cause of endogenous hypercortisolism. Pituitary surgery is the first-line treatment and bilateral adrenalectomy is the option of last resort due to its severe consequences.Observation: This is a 24-year-old patient followed for cushing disease revealed by a severe cushing syndrome, a urinary cortisol at 20 times normal and negative dexamethasone suppression test with a pituitary microadenoma on MRI. He was...

Introduction: Pituitary apoplexy is a serious medical complication of a pre-existing pituitary adenoma characterized by a variety of clinical symptoms ranging from mild headache to neurologically impaired and finally comatose patients.Case report : We report a case of apoplexy in a large prolactinoma resulting in empty sella syndrome with a successful pregnancy. Our patient is a 31-year-old female, with a history of macroprolactinoma for approximately 7y...

Introduction: Lymphocytic hypophysitis is a rare inflammatory disease of the pituitary gland of autoimmune origin, related to a diffuse infiltration of the pituitary gland sometimes leading to severe hypopituitarism. It is frequent in pregnant or postpartum women.Case report: A 28 year old female patient, followed up for pituitary microadenoma with prolactin for 5 years under dostinex 1 tablet/week who reported headaches with visual acuity decrease with ...

Introduction: Medical treatment of acromegaly with somatostatin analogues (SAs) has been used for a long time and is a well-established treatment in cases where surgery, which is the first-line treatment, is impossible or inadequate. We report a case of acromegaly under control after initiation of Lanreotide.Observation: Patient aged 59 years, referred for acromegaloid dysmorphic syndrome initially with tumor syndrome with IGF1 workup at 729 ng/mL (norma...

Introduction: Polyuro-polydipsia syndrome (PPS) is defined by urine excretion rate more than 3L per day, associated with a parallel increase in oral fluid intake. It poses problems of positive and etiological diagnosis. We discuss in this observation the modalities of exploration of PPS and its main etiologies.Case report: A 60-year-old patient, diabetic for 10 years, controlled on metformin, admitted for PPS evolving for 37 years. Clinical examination w...

Introduction: Steinert’s myotonic dystrophy (SMD) is a neuromuscular disorder with a multisystem distribution. It is a genetic disease with autosomal dominant transmission. It may be associated with various endocrine disorders.Observation: We report the case of a 47-year-old patient followed for DM since the age of 18, diabetic under insulin therapy for 20 years, hypertensive for 1 year under losartan 50 mg/d who was referred to us for evaluation of...

Introduction: Patients with PTC usually have excellent outcomes with appropriate therapy, while up to 30% of patients present with aggressive disease, including patients with locoregional recurrence and distant metastasis.The aim: Of this study is to analyze the characteristics of patients with papillary carcinoma of the thyroid with locoregional and distant recurrences.Résults: We included 12 cases of locoregional and distant...

Pendred syndrome, an autosomal recessive disorder, is the most common syndromal form of hearing loss and involves abnormalities of the cochlea, varying degrees of sensorineural hearing loss and diffuse thyroid enlargement/goiter. We describe a case of a delayed diagnosis of Pendred syndrome. The patient is a 30 years female who had a history of total thyroidectomy 13 years ago. And presented when aged 30 with a cervical abscess of ectopic thyroid under the submaxillary gland. ...

Introduction: Oculomotor palsies in diabetes are focal mononeuropathies. It is a diabetic neurological complication, relatively rare. The oculomotor nerves affected are mainly the external oculomotor nerve (VI), the common oculomotor nerve (III), and more rarely, the pathetic nerve (IV). We report the case of a type 2 diabetic patient in whom the diagnosis of oculomotor palsy was retained.Observation: This is a 65-year-old diabetic patient, 4 years old, ...